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CARACTERIZACION DE LA REGULACION TRANSCRIPCIONAL DE LA PARAOXONASA 1 (PON1) DE HUMANO EN CELULAS DE HEPATOCARCINOMA HUMANO (HEPG2)
(Universidad Autónoma de Nayarit, 2019)
Chemical characterization of polyphenol extracts from Andean and industrial Solanum tuberosum tubers and their cytotoxic activity on human hepatocarcinoma cells
(Sift Desk Journals, 2018-01)
Background: Polyphenols are plant metabolites that have been largely studied for their beneficial effect on human health. Potato is one of the most important crops worldwide and is a relevant source of human dietary nutrients ...
The functional activity of the miR-1914-5p in lipid metabolism of the hepatocarcinoma cell line HepG2: a potential molecular tool for controlling hepatic cellular migration
(Springer, 2021-04-28)
Hepatocellular carcinoma is one of the most common types of cancer in the world with high mortality rate and new therapies that control of fatty acid metabolism may limit the proliferation of cancer cells. In the last two ...
Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells
(ELSEVIER IRELAND LTDCLARE, 2013-08-02)
Engineered nanomaterials have been extensively applied as active materials for technological applications. Since the impact of these nanomaterials on health and environment remains undefined, research on their possible ...
Galectin-1 controls the proliferation and migration of liver Sinusoidal endothelial cells and their interaction with hepatocarcinoma cells
(Wiley, 2016-07)
Galectin-1 (Gal1), a beta-galactoside-binding protein elevated in hepatocellular carcinoma (HCC), promotes epithelial-mesenchymal transition (EMT) and its expression correlates with HCC growth, invasiveness and metastasis. ...
Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cells
(Nature Publishing Group, 2019-12)
The placental stem cells have called the focus of attention for their therapeutic potential to treat different diseases, including cancer. There is plenty evidence about the antiproliferative, antiangiogenic and proapoptotic ...
Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds
(Peerj Inc, 2016)
Marine organisms are a prolific source of drug leads in a variety of therapeutic areas. In the last few years, biomedical, pharmaceutical and nutraceutical industries have shown growing interest in novel compounds from ...
Estudo do potencial citotóxico e genotóxico do geraniol em células mononucleares do sangue periférico e de hepatocarcinoma humano HepG2
(Universidade Estadual Paulista (Unesp), 2017-02-20)
Os monoterpenos são compostos terpênicos não-nutritivos, conhecidos por possuírem atividade protetora contra doenças. São produzidos pelas plantas como metabólitos secundários, sendo os compostos de maior frequência nos ...
Cytotoxic, genotoxic, and oxidative stress-inducing effect of an L-amino acid oxidase isolated from Bothrops jararacussu venom in a co-culture model of HepG2 and HUVEC cells
(2019-04-15)
Hepatocellular carcinoma incidence rates have increased worldwide, which encouraged the development of new chemotherapeutic drugs. L-Amino acid oxidases from snake venoms are cytotoxic towards human tumor cells in in vitro ...
Avaliação da capacitação de quimioprevenção de Eugenia jambolana em linhagem de hepatocarcinoma celular (HepG2 e Hepa 1c1c7)
(Universidade Estadual Paulista (Unesp), 2012-05-18)
A variabilidade das regiões geográficas brasileiras favorece o desenvolvimento de diferentes espécies vegetais, o que estimula o estudo na busca de novos agentes bioativos. A quimioprevenção envolve o uso de substâncias ...